Brighter, more even skin
Fade Dark Spots, Even Skin Tone.
NanoMD® Cyntra™ 2.0 is a next-generation brightening cream powered by 8% cysteamine and tranexamic acid. Clinically developed to target melasma, hyperpigmentation, and stubborn dark patches with superior precision and improved tolerability.
Kick Start Your Glow
NanoMD® Cyntra™ 2.0 interrupts melanin production at multiple stages for faster, more consistent brightening. With Carrier-Effect™ delivery and Smart Matrix soothing technology, it makes powerful ingredients comfortable enough for daily use — even on sensitive skin.
Rapid Onset
Enhance Skin Tone
Superior Absorption
Slow Down Skin Aging
How NanoMD® Cyntra™ 2.0 Improves Skin Clarity
Cysteamine
Cyntra™ combines two powerhouse brightening actives to rebalance pigmentation safely and effectively.
Cysteamine (8%) — The Gold Standard
Cysteamine is a naturally occurring molecule in human cells. At therapeutic strength, it helps reduce the appearance of melasma and dark spots by regulating overactive pigment production at its biochemical source.
Tranexamic Acid — The Calm Behind the Clarity
This ingredient works by interrupting inflammatory and vascular signals that trigger stubborn pigmentation, helping prevent recurrence and supporting a more even tone. Together, they deliver a dual-action depigmenting effect proven to outperform conventional brightening creams.
After 1 Month of Cyntra
After 1 Month of Lumithion
Clinically proven to improve skin tone in 8 weeks
The Breakthrough: Smart Nanodelivery You Can Feel Working
Traditional creams struggle to penetrate the skin’s barrier. Cyntra™ changes that.
Carrier-Effect™ Nanodelivery
Ensures actives reach deeper layers where melanin is actually produced, improving speed and consistency of results.
Smart Matrix Technology
A soothing system designed to reduce irritation, minimise redness, and make daily usage comfortable — even at clinical-strength 8% cysteamine.
Contact UsCarrier-Effect™ Nanodelivery
Ensures actives reach deeper layers where melanin is actually produced, improving speed and consistency of results.
Smart Matrix Technology
A soothing system designed to reduce irritation, minimise redness, and make daily usage comfortable — even at clinical-strength 8% cysteamine.
Why Choose NanoMD® Cyntra™
NanoMD® CYNTRA™ uses advanced nanoencapsulation technology to deliver cysteamine and tranexamic acid (TXA) together — exactly where they’re needed in the skin.
Cysteamine is a well-studied, high-safety molecule naturally found in human cells. It helps reduce existing pigmentation and slows the formation of new dark spots. Tranexamic acid, an amino-acid derivative, works by calming the inflammatory and vascular signals that trigger melasma and excess pigment production.
When these two ingredients are delivered simultaneously in nano-sized carriers, TXA enhances the brightening power of cysteamine by slowing down the activity and growth of melanocytes — the cells responsible for producing pigment.
Cysteamine is a well-studied, high-safety molecule naturally found in human cells. It helps reduce existing pigmentation and slows the formation of new dark spots. Tranexamic acid, an amino-acid derivative, works by calming the inflammatory and vascular signals that trigger melasma and excess pigment production.
When these two ingredients are delivered simultaneously in nano-sized carriers, TXA enhances the brightening power of cysteamine by slowing down the activity and growth of melanocytes — the cells responsible for producing pigment.
Formula-stabilizing nano-encapsulation
Preserves ingredient potency, boosts skin penetration and reduces irritation for enhanced efficacy and comfort.
Carrier Effect™
The synergy of surface charge control and enzyme-drive release, guides actives deeper and releases them precisely when needed.
Smart Matrix
Forms a gel-like film that stabilizes actives, prolongs their contact and release, and soothes the skin.
Aspartame and Sugar-Free
No animal-derived ingredients - Suitable for diabetics and vegetarian.
Apply a thin layer once daily, or as directed by your clinic.
For best results:
- Use consistently for 8–12 weeks
- Follow with a gentle moisturiser if needed
- Use high-SPF sunscreen daily to maintain progress
Clinics often pair Cyntra™ with NanoMD® Lumithion™ for enhanced inside-out brightness.
Frequently Asked Questions
This section addresses any question about Lumithion. If you have more question, we’re always ready to help you out.
Contact UsWhat is NanoMD® Lumithion™?
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How does Lumithion™ work?
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What is glutathione and why is it important?
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How soon can I see results?
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Ready to Experience Bright Skin Backed by Science?
Rebuild your skin from within with biotech formulations trusted by medical professionals and loved by patients.
Contact UsReferences
- Khatri, Khalil A., et al. (2024). Efficacy, Safety, Satisfaction, Adherence to Treatment With Nano-Formulated Cysteamine Tranexamic Acid Cream to Treat Melasma. Journal of Drugs in Dermatology (JDD), 23(7), 529–537.
- Atallah, Carla, et al. (2022). Effect of cysteamine hydrochloride-loaded liposomes on skin depigmenting and penetration. European Journal of Pharmaceutical Sciences, 168, 106082.